Pentetic Acid

Pentetic Acid

SCHEMBL15950275

N.N.O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O.[MgH2]

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.88
▸ BLM P54132 2/20 0.88
▸ PMP22 Q01453 2/20 0.88
▸ KDM4E B2RXH2 2/20 0.88
▸ ALOX15 P16050 2/20 0.88
▸ LMNA P02545 1/20 0.88
▸ CHRM2 P08172 1/20 0.88
▸ ADRA2A P08913 1/20 0.88
▸ TSHR P16473 1/20 0.88
▸ DRD1 P21728 1/20 0.88
▸ SLC6A2 P23975 1/20 0.88
▸ SLC6A4 P31645 1/20 0.88
▸ CYP2C19 P33261 1/20 0.88
▸ ADRA1A P35348 1/20 0.88
▸ DRD3 P35462 1/20 0.88
▸ SLC6A3 Q01959 1/20 0.88
▸ HRH3 Q9Y5N1 1/20 0.88
▸ EYA2 O00167 1/20 0.82
▸ APP P05067 1/20 0.82
▸ ACE P12821 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentetic Acid SCHEMBL598927 0.97 TDP1 (0.94) TDP1BLMPMP22KDM4EALOX15
Pentetic Acid SCHEMBL11041213 0.97 TDP1 (0.94) TDP1BLMPMP22KDM4EALOX15
Edetic Acid SCHEMBL10891778 0.97 TDP1 (0.88) TDP1BLMPMP22KDM4EALOX15
Pentetic Acid SCHEMBL6241488 0.94 TDP1 (0.88) TDP1BLMPMP22KDM4EALOX15
Pentetic Acid SCHEMBL15950012 0.94 TDP1 (0.88) TDP1BLMPMP22KDM4EALOX15
Pentetic Acid SCHEMBL6566728 0.94 TDP1 (0.88) TDP1BLMPMP22KDM4EALOX15
Pentetic Acid SCHEMBL10888673 0.94 TDP1 (0.88) TDP1BLMPMP22KDM4EALOX15
Edetic Acid SCHEMBL3735469 0.94 TDP1 (0.93) TDP1BLMPMP22KDM4EALOX15
Edetic Acid SCHEMBL119008 0.94 TDP1 (0.93) TDP1BLMPMP22KDM4EALOX15
Edetic Acid SCHEMBL6249529 0.94 TDP1 (0.93) TDP1BLMPMP22KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768415-A Novel therapeutic and/or prophylactic agent for coronavirus infection (COVID-19) 日本纽翱医药股份有限公司 2023-03-07 — — CN disclosed
CN-111417390-A Pharmaceutical composition for enhancing antitumor effect of immune checkpoint inhibitor 思佰益药业股份有限公司 2020-07-14 — — CN disclosed
EP-2767276-B1 IMPROVING / PROPHYLACTIC AGENT FOR CHRONIC KIDNEY DISEASE SBI PHARMACEUTICALS CO LTD (JP) 2018-10-03 — — EP disclosed
US-9539225-B2 Anemia of cancer improving/prophylactic agent SBI PHARMACEUTICALS CO., LTD. (JP) 2017-01-10 — — US disclosed
US-9475755-B2 Prophylactic agent for chronic kidney disease SBI Pharmaceuticals Co., Ltd (JP) 2016-10-25 — — US disclosed
US-20140288173-A1 ANEMIA OF CANCER IMPROVING/PROPHYLACTIC AGENT SBI PHARMACEUTICALS CO., LTD. (JP) 2014-09-25 — — US disclosed
US-20140256806-A1 PROPHYLACTIC AGENT FOR CHRONIC KIDNEY DISEASE SBI PHARMACEUTICALS CO., LTD. (JP) 2014-09-11 — — US disclosed
EP-2767276-A1 IMPROVING / PROPHYLACTIC AGENT FOR CHRONIC KIDNEY DISEASE SBI Pharmaceuticals Co., Ltd. (JP) 2014-08-20 — — EP disclosed
EP-2767280-A1 ANEMIA OF CANCER IMPROVING / PROPHYLACTIC AGENT SBI Pharmaceuticals Co., Ltd. (JP) 2014-08-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140288173-A1 ANEMIA OF CANCER IMPROVING/PROPHYLACTIC AGENT ALAD, ASNS, AAAS TDP1 3004/4885BLM 3328/4885PMP22 3164/4885
US-20140256806-A1 PROPHYLACTIC AGENT FOR CHRONIC KIDNEY DISEASE ALAD, GLS, AAAS TDP1 3444/4885BLM 4024/4885PMP22 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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