Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454181 | 0.94 | SPHK1 (0.48) | SPHK1SMN1; SMN2PRCPTSHRGBA2 | |
| SCHEMBL19973666 | 0.83 | SPHK1 (0.39) | SPHK1TSHR | |
| SCHEMBL3388749 | 0.83 | SPHK1 (0.39) | SPHK1TSHR | |
| SCHEMBL8427865 | 0.83 | SPHK1 (0.39) | SPHK1TSHR | |
| SCHEMBL116264 | 0.83 | SPHK1 (0.39) | SPHK1TSHR | |
| SCHEMBL6846988 | 0.83 | SPHK1 (0.39) | SPHK1TSHR | |
| Hydrochloric Acid SCHEMBL953016 | 0.81 | SPHK1 (0.38) | SPHK1 | |
| Hydrochloric Acid SCHEMBL5578417 | 0.81 | SPHK1 (0.38) | SPHK1 | |
| Hydrochloric Acid SCHEMBL4489520 | 0.81 | SPHK1 (0.38) | SPHK1 | |
| SCHEMBL9768968 | 0.81 | ALDH1A1 (0.38) | SPHK1ALDH1A1ATMLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484720-A | A kind of antihypertensive active peptide Orn-Pro-Hyp and application and pharmaceutical composition | 南京大学 | 2018-09-04 | — | — | CN | disclosed |
| WO-2014127052-A1 | PERFLUORO-TERT-BUTYL HYDROXYPROLINE | ZONDLO NEAL (US) | 2014-08-21 | — | — | WO | disclosed |