Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955679 | 0.81 | SPHK1 (0.44) | ALDH1A1ATMLMNAPOLBSMN1; SMN2 | |
| SCHEMBL9768973 | 0.79 | ATM (0.40) | ALDH1A1ATMLMNAPOLBSMN1; SMN2 | |
| SCHEMBL7295736 | 0.77 | NAAA (0.45) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL454181 | 0.76 | SPHK1 (0.48) | SMN1; SMN2PRCPTSHRSPHK1NAAA | |
| SCHEMBL8276700 | 0.76 | SLC1A2 (0.51) | ALDH1A1ATMHCAR2CHRM2CHRM4 | |
| SCHEMBL9863068 | 0.76 | NAAA (0.42) | SMN1; SMN2PRCPTSHRHCAR2CHRM2 | |
| SCHEMBL9769032 | 0.74 | CHRM2 (0.37) | SMN1; SMN2PRCPTSHRHCAR2CHRM2 | |
| SCHEMBL9863070 | 0.74 | SLC1A2 (0.49) | PRCPHCAR2CHRM2CHRM4CHRM5 | |
| SCHEMBL7455916 | 0.72 | ALDH1A1 (0.37) | ALDH1A1ATMLMNAPOLBSMN1; SMN2 | |
| SCHEMBL8298807 | 0.71 | MEN1 (0.54) | ALDH1A1PRCPCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |