Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1772150 | 0.84 | CD44 (0.48) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL11954795 | 0.84 | GABRA1 (0.57) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL18535960 | 0.83 | ATM (0.46) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL282034 | 0.80 | TP53 (0.42) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL11225112 | 0.77 | CYP2A6 (0.45) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL2687017 | 0.77 | GABRA1 (0.48) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL8387574 | 0.77 | GABRA1 (0.48) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL15957634 | 0.76 | TRPA1 (0.44) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL6338910 | 0.74 | CD44 (0.48) | ATMTRPA1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL24478135 | 0.72 | CYP2A6 (0.41) | ATMTRPA1ALDH1A1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074506-A | 4' -halo-containing nucleotide and nucleoside therapeutic compositions and uses related thereto | 埃默里大学 | 2020-12-11 | — | — | CN | disclosed |
| US-8809451-B2 | Fluorinated dicarboxylic acid derivative and polymer obtained therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | MCCC2, AFF2, F13A1 | ATM 3040/4885TRPA1 176/4885ALDH1A1 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.