SCHEMBL15957645

SCHEMBL15957645

Cc1ccc(C(C)(O)C(F)(F)F)c(C)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.47
HSD11B1 P28845 2/20 0.34
PDK1 Q15118 4/20 0.33
PDK2 Q15119 4/20 0.33
PDK3 Q15120 4/20 0.33
PDK4 Q16654 4/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
DHODH Q02127 1/20 0.33
GLRA3 O75311 1/20 0.33
GLRB P48167 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
DAO P14920 2/20 0.33
HSP90AA1 P07900 1/20 0.32
KCNJ11 Q14654 1/20 0.32
METAP2 P50579 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13199190 0.85 AR (0.43) ARDHODHTDP1L3MBTL1DAO
SCHEMBL28630164 0.80 GLRA3 (0.47) MEN1KMT2AGLRA3GLRBTDP1
SCHEMBL15957688 0.78 AR (0.53) ARHSD11B1PDK1PDK2PDK3
SCHEMBL15957653 0.78 AR (0.69) ARHSD11B1
SCHEMBL13199328 0.77 DHODH (0.33) MEN1KMT2ADHODHGLRA3GLRB
SCHEMBL15957691 0.75 AR (0.53) ARHSD11B1PDK1PDK2PDK3
SCHEMBL15957638 0.75 AR (0.35) ARHSD11B1MEN1KMT2AGLRA3
SCHEMBL15957666 0.74 AR (0.51) ARHSD11B1MEN1KMT2A
SCHEMBL15831662 0.72 AR (0.58) ARHSD11B1KCNJ11
SCHEMBL1257806 0.71 METAP2 (0.45) MEN1KMT2ADHODHTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 AR 4258/4885HSD11B1 4548/4885PDK1 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.