Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.47 |
| ▸ | GLRB | P48167 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salycilic Acid SCHEMBL1457176 | 0.82 | GLRA3 (0.60) | GLRA3GLRBL3MBTL1TDP1DAO | |
| Salycilic Acid SCHEMBL29623842 | 0.82 | GLRA3 (0.60) | GLRA3GLRBL3MBTL1TDP1DAO | |
| SCHEMBL17896570 | 0.81 | GLRA3 (0.44) | GLRA3GLRBDAOGRIN2CMEN1 | |
| SCHEMBL18131276 | 0.81 | GLRA3 (0.44) | GLRA3GLRBL3MBTL1TDP1DAO | |
| SCHEMBL15957645 | 0.80 | AR (0.47) | GLRA3GLRBL3MBTL1TDP1DAO | |
| SCHEMBL31643852 | 0.78 | METAP2 (0.45) | L3MBTL1TDP1NOTUMMEN1KMT2A | |
| SCHEMBL1257806 | 0.78 | METAP2 (0.45) | L3MBTL1TDP1NOTUMMEN1KMT2A | |
| SCHEMBL13199190 | 0.78 | AR (0.43) | L3MBTL1TDP1DAO | |
| SCHEMBL30861725 | 0.77 | GLRA3 (0.63) | GLRA3GLRBL3MBTL1TDP1DAO | |
| SCHEMBL13199328 | 0.77 | DHODH (0.33) | GLRA3GLRBL3MBTL1TDP1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164468-A | Macrocyclic compounds and uses thereof | 思可海雅药品公司 | 2021-07-23 | — | — | CN | disclosed |