Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15957871 | 0.79 | — | — | |
| SCHEMBL361217 | 0.70 | L3MBTL1 (0.35) | L3MBTL1TSHRKDM4EATMKMT2A | |
| SCHEMBL10079931 | 0.67 | HTR2C (0.43) | L3MBTL1TSHR | |
| SCHEMBL15344551 | 0.64 | — | — | |
| SCHEMBL22485443 | 0.64 | HTR2C (0.32) | — | |
| SCHEMBL360012 | 0.62 | EPHX2 (0.33) | L3MBTL1TSHRALDH1A1TP53ATM | |
| SCHEMBL197612 | 0.61 | ALDH1A1 (0.48) | L3MBTL1TSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL198506 | 0.61 | ALDH1A1 (0.48) | L3MBTL1TSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL660922 | 0.60 | ALDH1A1 (0.54) | L3MBTL1TSHRALDH1A1KDM4ENPSR1 | |
| SCHEMBL1433202 | 0.60 | ALDH1A1 (0.62) | L3MBTL1TSHRALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809383-B2 | Pyrazole compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |