Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12050828 | 0.86 | POLB (0.43) | ALDH1A1KDM4ETDP1POLBNR1H4 | |
| SCHEMBL8998678 | 0.84 | HTT (0.43) | HTTALDH1A1RXRBKDM4ERXRA | |
| SCHEMBL13680103 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4ETDP1POLBAKR1C3 | |
| SCHEMBL28029961 | 0.81 | CA12 (0.49) | HTTALDH1A1KDM4E | |
| SCHEMBL7623240 | 0.81 | POLB (0.54) | HTTALDH1A1RXRBKDM4ERXRA | |
| SCHEMBL14182673 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL17618927 | 0.80 | ALDH1A1 (0.57) | HTTALDH1A1KDM4ETDP1POLB | |
| SCHEMBL634335 | 0.79 | HTT (0.65) | HTTALDH1A1KDM4EPOLBAKR1C3 | |
| SCHEMBL16263288 | 0.79 | LCK (0.44) | ALDH1A1KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL25845502 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ETDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884058-A | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | 阿奇克斯制药公司 | 2018-11-23 | — | — | CN | disclosed |
| US-9921498-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-03-20 | — | — | US | disclosed |
| US-20160377998-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-12-29 | — | — | US | disclosed |
| US-8808440-B2 | Ink composition, ink for inkjet recording and inkjet recording method | FUJIFILM CORPORATION (JP) | 2014-08-19 | — | — | US | disclosed |