Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263287 | 0.86 | LCK (0.41) | LCKFYNAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL13680103 | 0.83 | ALDH1A1 (0.56) | AKR1C3AKR1C2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL17618927 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL1180221 | 0.79 | LCK (0.58) | LCKFYNAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL27944766 | 0.79 | SMN1; SMN2 (0.53) | AKR1C3AKR1C2ALDH1A1KDM4EHPGD | |
| SCHEMBL15958587 | 0.79 | HTT (0.44) | AKR1C3AKR1C2ALDH1A1KDM4EPOLB | |
| SCHEMBL25845502 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL18875279 | 0.77 | KDM4E (0.42) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL10262241 | 0.77 | NPC1 (0.34) | ALDH1A1 | |
| SCHEMBL15425835 | 0.76 | PTGS2 (0.52) | LCKALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701841-B2 | Cell permeable, fluorescent dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-11 | — | — | US | disclosed |
| CN-106045962-A | Isoxazoline derivatives as pesticidal compounds | 先正达参股股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-08-11 | — | — | US | disclosed |
| US-9346957-B2 | Cell permeable, fluorescent dye | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2016-05-24 | — | — | US | disclosed |
| US-20140349282-A1 | Cell Permeable, Fluorescent Dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | EPCAM, IK, TSPO | LCK 4074/4885FYN 3521/4885AKR1C3 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.