Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12039989 | 0.81 | NPC1 (0.55) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL15958688 | 0.72 | RAB9A (0.47) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL13712159 | 0.72 | RAB9A (0.47) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL13609439 | 0.70 | NPC1 (0.51) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL17312265 | 0.69 | NPC1 (0.50) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL17312263 | 0.69 | NPC1 (0.50) | NPC1RAB9APOLBALDH1A1MAPT | |
| Iodide SCHEMBL17312325 | 0.68 | NPC1 (0.49) | NPC1RAB9APOLBALDH1A1MAPT | |
| Iodide SCHEMBL17312329 | 0.68 | NPC1 (0.49) | NPC1RAB9APOLBALDH1A1MAPT | |
| Bromide SCHEMBL29752811 | 0.68 | NPC1 (0.49) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL13416589 | 0.68 | MAOA (0.63) | NPC1RAB9APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8808824-B2 | Optical information recording medium, method of recording information and azo metal complex dye | FUJIFILM CORPORATION (JP) | 2014-08-19 | — | — | US | disclosed |