⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16382114 | 0.83 | — | — | |
| SCHEMBL15255414 | 0.73 | — | — | |
| SCHEMBL18533350 | 0.72 | TSHR (0.38) | — | |
| SCHEMBL5953080 | 0.71 | ALDH1A1 (0.40) | — | |
| SCHEMBL1851259 | 0.69 | — | — | |
| SCHEMBL18098180 | 0.67 | — | — | |
| SCHEMBL15759849 | 0.67 | — | — | |
| SCHEMBL1427272 | 0.67 | — | — | |
| SCHEMBL409239 | 0.65 | — | — | |
| SCHEMBL5522 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439968-B2 | Amine-containing lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-13 | — | — | US | disclosed |
| WO-2015172123-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | HADDACH MUSTAPHA (US) | 2015-11-12 | — | — | WO | disclosed |
| US-8808681-B2 | Crosslinked, degradable polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-08-19 | — | — | US | disclosed |