SCHEMBL5953080

SCHEMBL5953080

COCCC[N]CCCOC

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7067352 0.90 ALDH1A1 (0.44) ALDH1A1GAATSHR
SCHEMBL5933225 0.89 ALDH1A1 (0.34) ALDH1A1
SCHEMBL5933716 0.89 ALDH1A1 (0.39) ALDH1A1
SCHEMBL1796242 0.89
SCHEMBL2504826 0.85
SCHEMBL5932368 0.83 ALDH1A1 (0.39) ALDH1A1
SCHEMBL5911533 0.83 CA2 (0.38) ALDH1A1TSHR
SCHEMBL197370 0.79
SCHEMBL2515564 0.78 ALDH1A1 (0.55) ALDH1A1GAATSHR
SCHEMBL345679 0.78 ALDH1A1 (0.55) ALDH1A1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4490176-A PRINTING INKS, PAINTS; PIGMENT, ALKYLBENZENE SULFONIC ACID, HYDROXYNAPHTHALENE BASF AKTIENGESELLSCHAFT (DE) 1984-12-25 US claimed
EP-0076995-B1 LIQUID STABLE PREPARATIONS AND THEIR USE BASF Aktiengesellschaft (DE) 1984-07-11 EP claimed
EP-0043932-B1 LIQUID, STABLE PREPARATIONS OF PHTHALOCYANINE PIGMENTS OR INDANTHRON AND THEIR USE BASF Aktiengesellschaft (DE) 1984-04-18 EP claimed
EP-0076995-A1 Liquid stable preparations and their use BASF Aktiengesellschaft (DE) 1983-04-20 EP claimed
US-4350534-A Fluid, stable formulations of copper phthalocyanine or indanthrone BASF AKTIENGESELLSCHAFT (DE) 1982-09-21 US claimed
EP-0043932-A1 Liquid, stable preparations of phthalocyanine pigments or indanthron and their use BASF Aktiengesellschaft (DE) 1982-01-20 EP claimed
US-20060100269-A1 Use of 10-aminoaliphatyl-dibenz[b,f]oxepines for the treatment of degenerative ocular disorders LAMBROU GEORGE N 2006-05-11 US disclosed
EP-1589963-A1 USE OF 10-AMINOALIPHATYL-DIBENZ B,F OXEPINES FOR THE TR EATMENT OF DEGENERATIVE OCULAR DISORDERS Novartis AG (CH) 2005-11-02 EP disclosed
EP-1484191-A1 REWRITABLE OPTICAL INFORMATION RECORDING MEDIUM AND RECORDING/REPRODUCING METHOD, RECORDING/REPRODUCING DEVICE Sony Corporation (JP) 2004-12-08 EP disclosed
WO-2004066993-A1 USE OF 10-AMINOALIPHATYL-DIBENZ[B,F]OXEPINES FOR THE TREATMENT OF DEGENERATIVE OCULAR DISORDERS NOVARTIS AG (CH) 2004-08-12 WO disclosed
WO-2003057204-A2 MODULATION OF IAMT (PIMT OR PCMT) IN IMMUNE SYSTEM NORDIC BIOSCIENCE A/S (DK) 2003-07-17 WO disclosed
EP-1124903-B1 CATIONIC AZO-DYES BASF AG (DE) 2003-06-25 EP disclosed
US-6346609-B1 DISAZO DYES OR POLYAZO DYES BASF AKTIENGESELLSCHAFT (DE) 2002-02-12 US disclosed
EP-0090285-B1 PIGMENT PREPARATIONS AND THEIR USE IN PIGMENTING HELIOGRAPHIC AND LAC COLOURS BASF Aktiengesellschaft (DE) 1985-01-16 EP disclosed
US-4490176-A PRINTING INKS, PAINTS; PIGMENT, ALKYLBENZENE SULFONIC ACID, HYDROXYNAPHTHALENE BASF AKTIENGESELLSCHAFT (DE) 1984-12-25 US disclosed
EP-0076995-B1 LIQUID STABLE PREPARATIONS AND THEIR USE BASF Aktiengesellschaft (DE) 1984-07-11 EP disclosed
EP-0090285-A2 Pigment preparations and their use in pigmenting heliographic and lac colours BASF Aktiengesellschaft (DE) 1983-10-05 EP disclosed
EP-0076995-A1 Liquid stable preparations and their use BASF Aktiengesellschaft (DE) 1983-04-20 EP disclosed
US-4350534-A Fluid, stable formulations of copper phthalocyanine or indanthrone BASF AKTIENGESELLSCHAFT (DE) 1982-09-21 US disclosed
EP-0043932-A1 Liquid, stable preparations of phthalocyanine pigments or indanthron and their use BASF Aktiengesellschaft (DE) 1982-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100269-A1 Use of 10-aminoaliphatyl-dibenz[b,f]oxepines for the treatment of degenerative ocular disorders DBH, MAOB, AADAT ALDH1A1 793/4885GAA 3453/4885TSHR 1105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.