Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 7/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 6/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15959097 | 1.00 | PLA2G2A (0.36) | PLA2G2APLA2G10FEN1ELANECHEK1 | |
| SCHEMBL5187008 | 0.81 | KMT2A (0.41) | CHEK1MEN1RGS12USP2CYP1A2 | |
| SCHEMBL6932422 | 0.70 | CHEK1 (0.36) | CHEK1MEN1RGS12USP2CYP1A2 | |
| SCHEMBL6069711 | 0.69 | TYMS (0.54) | MEN1RGS12USP2CYP1A2POLB | |
| SCHEMBL29541 | 0.68 | PARP1 (0.50) | CHEK1MEN1RGS12USP2CYP1A2 | |
| SCHEMBL7598089 | 0.68 | PARP1 (0.50) | CHEK1MEN1RGS12USP2CYP1A2 | |
| SCHEMBL7601076 | 0.68 | PARP1 (0.50) | CHEK1MEN1RGS12USP2CYP1A2 | |
| SCHEMBL30606639 | 0.68 | PARP1 (0.50) | CHEK1MEN1RGS12USP2CYP1A2 | |
| SCHEMBL27516216 | 0.67 | CHEK1 (0.44) | PLA2G2ACHEK1 | |
| SCHEMBL11051768 | 0.66 | KMT2A (0.36) | MEN1RGS12USP2CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260035-B1 | POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF | CRYSOPTIX KK (JP) | 2014-08-20 | — | — | EP | disclosed |