Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14338181 | 1.00 | PTPRB (0.56) | PTPRBHPGDALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1596038 | 0.99 | PTPRB (0.55) | PTPRBHPGDALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1596040 | 0.99 | PTPRB (0.55) | PTPRBHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL25095078 | 0.89 | HPGD (0.57) | PTPRBHPGDALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL7744800 | 0.87 | HPGD (0.56) | PTPRBHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1595806 | 0.85 | SLC7A5 (0.56) | PTPRBHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1595807 | 0.85 | SLC7A5 (0.56) | PTPRBHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7902861 | 0.81 | ALDH1A1 (0.49) | PTPRBALDH1A1 | |
| SCHEMBL31369739 | 0.81 | SLC7A5 (0.51) | HPGDALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL12727039 | 0.81 | PTPRB (0.55) | PTPRBHPGDALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919515-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2011-04-05 | — | — | US | disclosed |
| US-7919515-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2011-04-05 | — | — | US | disclosed |
| US-7629370-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2009-12-08 | — | — | US | disclosed |
| US-7629370-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2009-12-08 | — | — | US | disclosed |
| EP-1874745-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA RECEPTOR LIGANDS | Adamed SP. Z O.O. (PL) | 2008-01-09 | — | — | EP | disclosed |
| US-7312338-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-12-25 | — | — | US | disclosed |
| US-7309791-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z.O.O (PL) | 2007-12-18 | — | — | US | disclosed |
| US-7309791-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z.O.O (PL) | 2007-12-18 | — | — | US | disclosed |
| US-20070219259-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | ADAMED SP. Z O.O. (PL) | 2007-09-20 | — | — | US | disclosed |
| US-20070219259-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | ADAMED SP. Z O.O. (PL) | 2007-09-20 | — | — | US | disclosed |
| US-20070161799-A1 | 3-Phenylpropionic acid derivatives | ADAMED, SP. Z O.O. (PL) | 2007-07-12 | — | — | US | disclosed |
| US-20070161799-A1 | 3-Phenylpropionic acid derivatives | ADAMED, SP. Z O.O. (PL) | 2007-07-12 | — | — | US | disclosed |
| US-7220766-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-05-22 | — | — | US | disclosed |
| US-7220766-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-05-22 | — | — | US | disclosed |
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-04-19 | — | — | US | disclosed |
| WO-2006077206-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA REZEPTOR LIGANDEN | ADAMED SP. Z O.O. (PL) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006077217-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | ADAMED SP. Z O.O. (PL) | 2006-07-27 | — | — | WO | disclosed |
| US-20060160870-A1 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2006-07-20 | — | — | US | disclosed |
| US-20060160868-A1 | 3-Phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2006-07-20 | — | — | US | disclosed |
| WO-2006067086-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | ADAMED SP. Z O.O. (PL) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | PPARA, PPARD, PPARG | PTPRB 1454/4885HPGD 924/4885ALDH1A1 957/4885 |
| US-20070161799-A1 | 3-Phenylpropionic acid derivatives | PAOX, PPARA, PPARG | PTPRB 1374/4885HPGD 384/4885ALDH1A1 714/4885 |
| US-20060160870-A1 | 3-phenylpropionic acid derivatives | PPARA, PPARG, PPARD | PTPRB 1493/4885HPGD 787/4885ALDH1A1 846/4885 |
| US-20060160868-A1 | 3-Phenylpropionic acid derivatives | PPARA, PPARG, PPARD | PTPRB 1484/4885HPGD 619/4885ALDH1A1 844/4885 |
| US-20070219259-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | PPARA, PPARD, PPARG | PTPRB 1547/4885HPGD 1010/4885ALDH1A1 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.