Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7744800 | 0.99 | HPGD (0.56) | HPGDRECQLLMNAALDH1A1KDM4E | |
| SCHEMBL14338181 | 0.89 | PTPRB (0.56) | HPGDRECQLLMNAALDH1A1KDM4E | |
| SCHEMBL1596041 | 0.89 | PTPRB (0.56) | HPGDRECQLLMNAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1596038 | 0.87 | PTPRB (0.55) | HPGDRECQLLMNAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1596040 | 0.87 | PTPRB (0.55) | HPGDRECQLLMNAALDH1A1KDM4E | |
| SCHEMBL9437458 | 0.84 | ALDH1A1 (0.48) | HPGDRECQLALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL9437459 | 0.84 | ALDH1A1 (0.48) | HPGDRECQLALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL7960935 | 0.83 | SLC7A5 (0.48) | ALDH1A1 | |
| SCHEMBL25095198 | 0.83 | LMNA (0.63) | HPGDRECQLLMNAALDH1A1KDM4E | |
| SCHEMBL1595807 | 0.82 | SLC7A5 (0.56) | HPGDRECQLLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025861-A1 | NEW VASHS INHIBITORS, CONJUGATES THEREOF AND THEIR USES AS DRUGS OR AS RESEARCH TOOLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2023-03-02 | — | — | WO | disclosed |