SCHEMBL15964432

SCHEMBL15964432

c1ccc(N(c2ccc3c4ccccc4n(-c4ccccc4)c3c2)c2ccc3c4ccccc4n(-c4ccccc4)c3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
ATM Q13315 1/20 0.60
MAPK8 P45983 2/20 0.39
HSD17B10 Q99714 1/20 0.38
KDR P35968 1/20 0.38
ALDH1A1 P00352 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
MAPT P10636 2/20 0.37
CYP2D6 P10635 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
REN P00797 1/20 0.36
PGR P06401 2/20 0.36
KMT2A Q03164 2/20 0.36
IL1R1 P14778 1/20 0.36
GLA P06280 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19738242 1.00 KDM4E (0.60) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL22989359 1.00 KDM4E (0.60) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL11922086 1.00 KDM4E (0.60) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL11922009 0.98 KDM4E (0.58) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL24729779 0.98 KDM4E (0.62) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL11922004 0.97 KDM4E (0.56) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL11921989 0.97 KDM4E (0.55) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL24514833 0.97 KDM4E (0.60) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL11922019 0.95 KDM4E (0.55) KDM4EL3MBTL1ATMMAPK8HSD17B10
SCHEMBL20904347 0.95 KDM4E (0.55) KDM4EL3MBTL1ATMMAPK8HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49237-E1 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2022-10-04 US disclosed
US-10937967-B2 Amine-based compound and organic light-emitting device including the amine-based compound SAMSUNG DISPLAY CO., LTD. (KR) 2021-03-02 US disclosed
US-20190115543-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-18 US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US disclosed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10937967-B2 Amine-based compound and organic light-emitting device including the amine-based compound AOC2, AOC1, SAT1 KDM4E 495/4885L3MBTL1 665/4885ATM 792/4885
US-20190115543-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND AOC2, AOC1, SAT1 KDM4E 495/4885L3MBTL1 665/4885ATM 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.