Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15964920 | 0.89 | MAPT (0.39) | TRPV1POLBSMN1; SMN2KMT2ASTING1 | |
| SCHEMBL15964652 | 0.81 | PDE3B (0.50) | POLBSMN1; SMN2PDE3BPDE3AMAPT | |
| SCHEMBL22368731 | 0.77 | BRD4 (0.63) | BRD4CREBBPPOLBSMN1; SMN2NPC1 | |
| SCHEMBL3485856 | 0.76 | FABP6 (0.43) | KMT2AMAPT | |
| SCHEMBL23189095 | 0.75 | BRD4 (0.45) | BRD4CREBBPPDE3BPDE3AMAOB | |
| SCHEMBL22368809 | 0.75 | BRD4 (0.63) | BRD4CREBBPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22369086 | 0.74 | MAOB (0.65) | BRD4CREBBPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL18794868 | 0.74 | MAOB (0.48) | BRD4CREBBPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28575263 | 0.73 | CA9 (0.51) | BRD4CREBBPPOLBSMN1; SMN2PDE3B | |
| SCHEMBL24720317 | 0.73 | CMA1 (0.45) | BRD4PDE3BPDE3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014125444-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2014-08-21 | — | — | WO | disclosed |