Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 7/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 7/20 | 0.42 |
| ▸ | HTR2C | P28335 | 11/20 | 0.41 |
| ▸ | HTR2B | P41595 | 9/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128506 | 0.81 | CDK5 (0.47) | CDK5CDK5R1HTR2CHTR2BCCNA2 | |
| SCHEMBL12356425 | 0.81 | CDK5 (0.42) | CDK5CDK5R1HTR2CHTR2BCCNA2 | |
| SCHEMBL12356426 | 0.81 | CDK5 (0.42) | CDK5CDK5R1HTR2CHTR2BCCNA2 | |
| SCHEMBL10272062 | 0.81 | CDK5 (0.47) | CDK5CDK5R1HTR2CHTR2BCCNA2 | |
| SCHEMBL24197819 | 0.79 | CDK5 (0.46) | CDK5CDK5R1HTR2CHTR2BCCNA2 | |
| SCHEMBL12826117 | 0.79 | CDK5 (0.46) | CDK5CDK5R1HTR2CHTR2BCCNA2 | |
| SCHEMBL4595953 | 0.77 | HTR2C (0.41) | CDK5CDK5R1HTR2CHTR2BCCNA2 | |
| SCHEMBL10272451 | 0.77 | CDK5 (0.43) | CDK5CDK5R1HTR2CHTR2BCCNA2 | |
| SCHEMBL29564444 | 0.74 | CDK5 (0.46) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL10013082 | 0.74 | CDK5 (0.46) | CDK5CDK5R1CCNA2CDK2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919528-B2 | Antibiotic; bactericides | GLAXOSMITHKLINE LLC (US) | 2011-04-05 | — | — | US | disclosed |
| EP-1509218-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-26 | — | — | EP | disclosed |
| US-20050222412-A1 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2005-10-06 | — | — | US | disclosed |
| EP-1509218-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222412-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | CDK5 2144/4885CDK5R1 2306/4885HTR2C 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.