Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15965438 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL29098152 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL7712786 | 0.95 | — | — | |
| SCHEMBL15965442 | 0.91 | ALDH1A1 (0.64) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL15071693 | 0.91 | ALDH1A1 (0.64) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL15965439 | 0.91 | ALDH1A1 (0.64) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL10962985 | 0.88 | KDM4E (0.47) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL10381823 | 0.88 | TSHR (0.49) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL11806304 | 0.88 | TSHR (0.49) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL5933120 | 0.88 | KDM4E (0.47) | ALDH1A1TSHRKDM4ERECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |