⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098152 | 0.95 | ALDH1A1 (0.50) | — | |
| SCHEMBL15965438 | 0.95 | ALDH1A1 (0.50) | — | |
| SCHEMBL15965448 | 0.95 | ALDH1A1 (0.50) | — | |
| Diethanolamine SCHEMBL9560408 | 0.87 | ALDH1A1 (0.48) | — | |
| SCHEMBL239490 | 0.87 | ALDH1A1 (0.45) | — | |
| SCHEMBL15071693 | 0.86 | ALDH1A1 (0.64) | — | |
| SCHEMBL28564770 | 0.86 | ALDH1A1 (0.50) | — | |
| SCHEMBL15965439 | 0.86 | ALDH1A1 (0.64) | — | |
| SCHEMBL15965442 | 0.86 | ALDH1A1 (0.64) | — | |
| Diethanolamine SCHEMBL8961797 | 0.84 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-11807643-B2 | Fluorescent dyes | CEPHEID (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230146675-A1 | PYRIMIDO[5,4-d]PYRIMIDINE DERIVATIVES AS ENT INHIBITORS FOR THE TREATMENT OF CANCERS, AND COMBINATION THEREOF WITH ADENOSINE RECEPTOR ANTAGONISTS | iTeos Belgium SA (BE) | 2023-05-11 | — | — | US | disclosed |
| US-20220017531-A1 | FLUORESCENT DYES | CEPHEID (US) | 2022-01-20 | — | — | US | disclosed |
| US-20210393792-A1 | ANTIBODY-CONJUGATES FOR TARGETING OF TUMOURS EXPRESSING TROP-2 | SYNAFFIX B.V. (NL) | 2021-12-23 | — | — | US | disclosed |
| CN-107850859-B | Stripping composition for removing photoresist on semiconductor substrate | 富士胶片电子材料美国有限公司 | 2021-06-01 | — | — | CN | disclosed |
| US-10875840-B2 | Methods for inducing bioorthogonal reactivity | UNIVERSITY OF DELAWARE (US) | 2020-12-29 | — | — | US | disclosed |
| US-10858342-B2 | Bicyclic imidazole derivatives useful for the treatment of renal diseases, cardiovascular diseases and fibrotic diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-12-08 | — | — | US | disclosed |
| US-10676467-B2 | Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof | WASHINGTON UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190231815-A1 | COMPOSITIONS COMPRISING COPPER CHELATORS AND METHODS OF USE THEREOF FOR TREATING VASCULOPATHIES | REVERSPAH LLC | 2019-08-01 | — | — | US | disclosed |
| US-9777020-B2 | Furo-3-carboxamide derivatives and methods of use | ABBVIE INC. (US) | 2017-10-03 | — | — | US | disclosed |
| EP-3097095-A1 | FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE | AbbVie Inc. (US) | 2016-11-30 | — | — | EP | disclosed |
| US-20150210720-A1 | FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE | ABBVIE INC. | 2015-07-30 | — | — | US | disclosed |
| WO-2015112754-A1 | FURO-3-CARBOXAMIDE DERIVATIVES AND METHODS OF USE | ABBVIE INC. (US) | 2015-07-30 | — | — | WO | disclosed |
| US-7572777-B2 | Florfenicol prodrug having improved water solubility | SCHERING-PLOUGH ANIMAL HEALTH CORP. (US) | 2009-08-11 | — | — | US | disclosed |
| US-20070021387-A1 | Florfenicol prodrug having improved water solubility | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2007-01-25 | — | — | US | disclosed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |
| US-4223138-A | VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |