Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.40 |
| ▸ | RARG | P13631 | 8/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15965501 | 0.88 | RARG (0.34) | PTPN11RARGRARARARBKMT2A | |
| SCHEMBL15965506 | 0.87 | PTPN11 (0.38) | PTPN11RARGRARARARBALDH1A1 | |
| SCHEMBL15965507 | 0.86 | ALDH1A1 (0.49) | PTPN11RARARARBALDH1A1KMT2A | |
| SCHEMBL15965503 | 0.81 | PDK2 (0.34) | PTPN11RARGRARARARBALDH1A1 | |
| SCHEMBL14929447 | 0.80 | ALDH1A1 (0.40) | RARGRARARARBALDH1A1KMT2A | |
| SCHEMBL15966201 | 0.78 | PTPN11 (0.45) | PTPN11RARGALDH1A1KMT2APTK2B | |
| SCHEMBL15965464 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KMT2APTK2BSLC6A9PTPN1 | |
| SCHEMBL15965505 | 0.77 | PTPN11 (0.41) | PTPN11RARGRARARARBALDH1A1 | |
| SCHEMBL20998171 | 0.77 | KMT2A (0.36) | PTPN11RARGRARARARBALDH1A1 | |
| SCHEMBL15965504 | 0.76 | KMT2A (0.47) | PTPN11ALDH1A1KMT2APTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |