Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929447 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KMT2APTK2BRARGKDM4E | |
| SCHEMBL15966203 | 0.83 | PTPN11 (0.41) | PTPN11ALDH1A1KMT2APTK2BMAPK1 | |
| SCHEMBL15966204 | 0.82 | PTPN11 (0.40) | PTPN11ALDH1A1KMT2APTK2BMAPK1 | |
| SCHEMBL15965481 | 0.81 | L3MBTL1 (0.39) | KMT2AMAPK1NPC1RAB9AGAA | |
| SCHEMBL23048986 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KMT2APTK2BMAPK1NPSR1 | |
| SCHEMBL15966202 | 0.80 | MAPT (0.33) | ALDH1A1KMT2AMAPK1NPSR1HTT | |
| SCHEMBL20998171 | 0.78 | KMT2A (0.36) | PTPN11ALDH1A1KMT2APTK2BRARG | |
| SCHEMBL15965502 | 0.78 | PTPN11 (0.40) | PTPN11ALDH1A1KMT2APTK2BRARG | |
| SCHEMBL15965480 | 0.78 | AR (0.37) | ALDH1A1KMT2AMAPK1NPC1CYP2C9 | |
| SCHEMBL15965465 | 0.78 | AR (0.37) | ALDH1A1KMT2AMAPK1NPC1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |