SCHEMBL15965629

SCHEMBL15965629

CCC1O[C@@H](O[C@@H]2C(OC(=O)c3ccccc3)[C@H](O[C@@H]3C(CC)O[C@@H](OCc4ccccc4)C(OC(=O)c4ccccc4)[C@H]3C)OC(COC(=O)c3ccccc3)[C@@H]2OC(=O)c2ccccc2)C(NC(C)=O)[C@@H](C)[C@@H]1O[C@@H]1OC(COC(=O)c2ccccc2)[C@H](O)[C@H](O)C1OC(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.41
▸ LMNA P02545 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ SELP P16109 5/20 0.36
▸ FGF2 P09038 3/20 0.36
▸ MDK P21741 1/20 0.36
▸ FGF1 P05230 2/20 0.36
▸ VEGFA P15692 2/20 0.36
▸ HPSE Q9Y251 2/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ USP2 O75604 1/20 0.35
▸ NT5E P21589 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ MDM2 Q00987 1/20 0.34
▸ SELE P16581 1/20 0.34
▸ PTPN1 P18031 1/20 0.34
▸ TYMP P19971 1/20 0.34
▸ MAG P20916 1/20 0.34
▸ ANTXR2 P58335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965627 0.93 POLB (0.47) POLBLMNAKMT2AMEN1USP2
SCHEMBL15965614 0.91 POLB (0.46) POLBLMNAKMT2AFGF2MDK
SCHEMBL15965619 0.90 TYMP (0.40) POLBKMT2ASELPFGF2FGF1
SCHEMBL15965624 0.89 ALDH1A1 (0.41) POLBLMNAKMT2ASELPFGF2
SCHEMBL15965620 0.87 POLB (0.47) POLBLMNAKMT2AFGF2MDK
SCHEMBL15965625 0.87 POLB (0.44) POLBLMNAKMT2AFGF2MDK
SCHEMBL15965626 0.87 LGALS3 (0.44) SELPSELEMAG
SCHEMBL15965622 0.86 POLB (0.46) POLBLMNAKMT2ASELPSELE
SCHEMBL15965618 0.84 POLB (0.42) POLBLMNAKMT2AFGF2MDK
SCHEMBL15081192 0.82 POLB (0.58) POLBLMNAKMT2AFGF2FGF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140235850-A1 SYNTHESIS OF HMO CORE STRUCTURES GLYCOM A/S (DK) 2014-08-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235850-A1 SYNTHESIS OF HMO CORE STRUCTURES GNE, OGT, GALE POLB 1235/4885LMNA 1294/4885KMT2A 3468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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