SCHEMBL15965690

SCHEMBL15965690

c1ccc(-c2ccc3oc4ccc(-n5c6ccccc6c6ncccc65)cc4c3c2)c(-c2ccc3oc4ccc(-n5c6ccccc6c6ncccc65)cc4c3c2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
MAPT P10636 2/20 0.35
PDE4D Q08499 5/20 0.34
KDM4E B2RXH2 4/20 0.33
ALOX5 P09917 1/20 0.32
NCOA1 Q15788 1/20 0.32
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
HTT P42858 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ACVR1 Q04771 2/20 0.31
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
COMT P21964 1/20 0.30
ALDH1A1 P00352 2/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
TNIK Q9UKE5 1/20 0.30
BMPR1B O00238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965697 0.94 MAPT (0.38) NPC1MAPTPDE4DKDM4EALOX5
SCHEMBL10348765 0.94 NPC1 (0.37) NPC1MAPTPDE4DKDM4ENCOA1
SCHEMBL15965707 0.93 KMO (0.35) NPC1MAPTPDE4DKDM4EALOX5
SCHEMBL10348766 0.93 NPC1 (0.36) NPC1MAPTPDE4DKDM4ENCOA1
SCHEMBL16606295 0.92 MAPK14 (0.33) NPC1MAPTPDE4D
SCHEMBL17264917 0.92 MAPK14 (0.33) NPC1MAPTPDE4D
SCHEMBL15965730 0.91 RPS6KA3 (0.33) NPC1MAPTPDE4D
SCHEMBL4570442 0.91 MAPT (0.40) NPC1MAPTPDE4DKDM4ENCOA1
SCHEMBL13471329 0.91 NPC1 (0.30) NPC1MAPT
SCHEMBL10041352 0.91 PLA2G2A (0.36) NPC1MAPTPDE4DKDM4ENCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140231772-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 US disclosed
US-20140231772-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 US disclosed