Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 7/20 | 0.33 |
| ▸ | MMP3 | P08254 | 7/20 | 0.33 |
| ▸ | NAAA | Q02083 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596363 | 0.77 | HDAC3 (0.36) | MEN1LMNAMAPTKMT2AHDAC3 | |
| SCHEMBL5641213 | 0.74 | SRC (0.43) | MMP1MMP3SRCF10CCR2 | |
| SCHEMBL6224777 | 0.74 | SRC (0.43) | MMP1MMP3SRCF10CCR2 | |
| SCHEMBL15966510 | 0.74 | HDAC1 (0.56) | FPR2SRCKMT2AHDAC1HDAC8 | |
| SCHEMBL13464988 | 0.74 | MMP1 (0.43) | MMP1MMP3SRCF2F10 | |
| SCHEMBL9980205 | 0.71 | ACE (0.51) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL4594212 | 0.70 | PIK3CD (0.55) | MAPT | |
| SCHEMBL1551140 | 0.70 | CYP3A4 (0.35) | MEN1MAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL10264999 | 0.69 | F2 (0.47) | FPR2MEN1KMT2AF2F10 | |
| SCHEMBL8234664 | 0.69 | F2 (0.50) | FPR2MMP1MMP3F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957555-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2015-12-23 | — | — | EP | disclosed |
| EP-2957555-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2015-12-23 | — | — | EP | disclosed |
| WO-2014125145-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2014-08-21 | — | — | WO | disclosed |