Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27425673 | 0.78 | FKBP1A (0.52) | FKBP1ACYP1A2HIF1AMEN1KMT2A | |
| SCHEMBL15966508 | 0.77 | FPR2 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5048047 | 0.74 | FKBP1A (0.40) | FKBP1ACYP1A2HIF1ANPSR1MEN1 | |
| SCHEMBL19559460 | 0.72 | MAPT (0.44) | SLC6A4SLC6A3SLC6A2CYP1A2HIF1A | |
| SCHEMBL4594212 | 0.72 | PIK3CD (0.55) | ALDH1A1MAPT | |
| SCHEMBL3105740 | 0.72 | BRD4 (0.44) | FKBP1ASLC6A4SLC6A3SLC6A2CYP1A2 | |
| SCHEMBL1551140 | 0.72 | CYP3A4 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15656372 | 0.71 | FKBP1A (0.35) | FKBP1ASLC6A4SLC6A3SLC6A2CYP1A2 | |
| SCHEMBL19559454 | 0.70 | CYP1A2 (0.38) | SLC6A4SLC6A3SLC6A2CYP1A2HIF1A | |
| SCHEMBL1531470 | 0.70 | BRD4 (0.55) | ALDH1A1MAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10420849-B2 | Pyrrolidone derivatives, oligomers and polymers | NANOSYNTHONS LLC (US) | 2019-09-24 | — | — | US | disclosed |
| US-20170246323-A1 | PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS | NANOSYNTHONS LLC (US) | 2017-08-31 | — | — | US | disclosed |
| EP-3194365-A1 | PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS | Nanosynthons LLC (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016040962-A1 | PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS | NANOSYNTHONS LLC (US) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170246323-A1 | PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS | POF1B, VGF, RAB5IF | HDAC3 3455/4885HDAC4 4737/4885HDAC1 4328/4885 |
| US-10420849-B2 | Pyrrolidone derivatives, oligomers and polymers | POF1B, VGF, RAB5IF | HDAC3 3455/4885HDAC4 4737/4885HDAC1 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.