⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11560304 | 0.75 | — | — | |
| SCHEMBL18530850 | 0.75 | HSD17B10 (0.36) | — | |
| SCHEMBL9276264 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL22024100 | 0.73 | PIK3CD (0.36) | — | |
| SCHEMBL13966613 | 0.71 | — | — | |
| SCHEMBL5638153 | 0.69 | — | — | |
| SCHEMBL22131416 | 0.69 | MAPK1 (0.32) | — | |
| SCHEMBL11030675 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL24658751 | 0.67 | — | — | |
| SCHEMBL669347 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573978-B2 | Cyclosporin derivatives for the treatment and prevention of a viral infection | S&T GLOBAL, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9504728-B2 | Dosage form | NEUROVIVE PHARMACEUTICAL AB (SE) | 2016-11-29 | — | — | US | disclosed |
| US-9119853-B2 | Sanglifehrin based compounds | NEUROVIVE PHARMACEUTICAL AB (SE) | 2015-09-01 | — | — | US | disclosed |
| US-20140234414-A1 | Novel Dosage Form | Abliva Ab (SE) | 2014-08-21 | — | — | US | disclosed |