Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 5/20 | 0.69 |
| ▸ | CTSL | P07711 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | TUBB | P07437 | 1/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001723 | 0.83 | CTSV (0.75) | CTSVCTSLHPGDLMNAKDM4E | |
| SCHEMBL367268 | 0.82 | HPGD (1.00) | CTSVCTSLHPGDLMNAKDM4E | |
| SCHEMBL29411863 | 0.82 | HPGD (1.00) | CTSVCTSLHPGDLMNAKDM4E | |
| SCHEMBL2789486 | 0.78 | CYP19A1 (1.00) | HPGDKDM4EHSD17B10CYP19A1RAB9A | |
| SCHEMBL29790209 | 0.78 | CYP19A1 (1.00) | HPGDKDM4EHSD17B10CYP19A1RAB9A | |
| Hydrochloric Acid SCHEMBL27830550 | 0.76 | CYP19A1 (0.97) | HPGDKDM4EHSD17B10CYP19A1RAB9A | |
| SCHEMBL21563920 | 0.76 | CYP19A1 (0.51) | CYP19A1KMT2AADORA2AADORA1ALDH1A1 | |
| SCHEMBL26847017 | 0.76 | CTSV (0.56) | CTSVCTSLHPGDLMNAKDM4E | |
| SCHEMBL2791999 | 0.76 | CYP19A1 (0.59) | LMNAKDM4ECYP19A1CYP11B1CYP11B2 | |
| Acetic Acid SCHEMBL6142950 | 0.75 | HPGD (0.84) | CTSVCTSLHPGDLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014128206-A1 | COMPOUNDS FOR USE IN INHIBITING HIV CAPSID ASSEMBLY | Ruprecht-Karls-Universität Heidelberg (DE) | 2014-08-28 | — | — | WO | disclosed |
| WO-2014128206-A1 | COMPOUNDS FOR USE IN INHIBITING HIV CAPSID ASSEMBLY | Ruprecht-Karls-Universität Heidelberg (DE) | 2014-08-28 | — | — | WO | disclosed |
| EP-2769723-A1 | Compounds for use in inhibiting HIV capsid assembly | Ruprecht-Karls-Universität Heidelberg (DE) | 2014-08-27 | — | — | EP | disclosed |
| EP-2769723-A1 | Compounds for use in inhibiting HIV capsid assembly | Ruprecht-Karls-Universität Heidelberg (DE) | 2014-08-27 | — | — | EP | disclosed |