Phenylalanine

Phenylalanine

SCHEMBL15966897

Cc1cccc(C)c1C[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 7/20 0.71
ALPI P09923 1/20 0.71
PKM P14618 1/20 0.71
PTGS1 P23219 1/20 0.71
XIAP P98170 1/20 0.71
SLC1A3 P43003 2/20 0.53
SLC1A2 P43004 2/20 0.53
SLC1A1 P43005 2/20 0.53
NOS3 P29474 2/20 0.52
NOS1 P29475 2/20 0.52
NOS2 P35228 2/20 0.52
GRIA2 P42262 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
SLC15A1 P46059 1/20 0.49
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19667341 0.92 SLC7A5 (0.55) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL2703289 0.92 SLC7A5 (0.55) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL38535 0.92 SLC7A5 (0.55) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL10477485 0.90 SLC7A5 (0.53) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL10477486 0.90 SLC7A5 (0.53) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL28570383 0.88 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28570385 0.88 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8609036 0.84 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28298768 0.84 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL8609032 0.84 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3167935-B1 METHOD AND CARRIER COMPLEXES FOR DELIVERING MOLECULES TO CELLS CORNELL RES FOUNDATION INC (US) 2018-07-18 EP disclosed
EP-2604287-B1 Method and Carrier Complexes for Delivering Molecules to Cells CORNELL RES FOUNDATION INC (US) 2016-12-07 EP disclosed
EP-2604621-B1 Method and carrier complexes for delivering molecules to cells CORNELL RES FOUNDATION INC (US) 2015-10-21 EP disclosed
EP-2604285-B1 Method and Carrier Complexes for Delivering Molecules to Cells CORNELL RES FOUNDATION INC (US) 2014-08-27 EP disclosed
EP-2604286-B1 Method and Carrier Complexes for Delivering Molecules to Cells CORNELL RES FOUNDATION INC (US) 2014-08-27 EP disclosed