Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2703289 | 1.00 | SLC7A5 (0.55) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL38535 | 1.00 | SLC7A5 (0.55) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL10477485 | 0.98 | SLC7A5 (0.53) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL10477486 | 0.98 | SLC7A5 (0.53) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL15966897 | 0.92 | SLC7A5 (0.71) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL38803 | 0.90 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL38804 | 0.90 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL20889265 | 0.88 | SLC7A5 (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL22864320 | 0.85 | SLC7A5 (0.41) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7774176 | 0.84 | SLC7A5 (0.44) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464324-B1 | ANGIOTENSIN-1-RECEPTOR ANTAGONISTS | FERRING BV (NL) | 2021-04-07 | — | — | EP | claimed |
| US-20200102348-A1 | ANGIOTENSIN-1-RECEPTOR ANTAGONISTS | FERRING B.V. (NL) | 2020-04-02 | — | — | US | claimed |
| US-10344054-B2 | Angiotensin-1-receptor antagonists | FERRING B.V. (NL) | 2019-07-09 | — | — | US | claimed |
| US-20170349629-A1 | Angiotensin-1-Receptor Antagonists | FERRING B.V. (NL) | 2017-12-07 | — | — | US | claimed |
| EP-3464324-B1 | ANGIOTENSIN-1-RECEPTOR ANTAGONISTS | FERRING BV (NL) | 2021-04-07 | — | — | EP | disclosed |
| US-20200102348-A1 | ANGIOTENSIN-1-RECEPTOR ANTAGONISTS | FERRING B.V. (NL) | 2020-04-02 | — | — | US | disclosed |
| US-10344054-B2 | Angiotensin-1-receptor antagonists | FERRING B.V. (NL) | 2019-07-09 | — | — | US | disclosed |
| EP-3464324-A1 | ANGIOTENSIN-1-RECEPTOR ANTAGONISTS | Ferring B.V. (NL) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017207760-A1 | ANGIOTENSIN-1-RECEPTOR ANTAGONISTS | FERRING B.V. (NL) | 2017-12-07 | — | — | WO | disclosed |
| US-20170349629-A1 | Angiotensin-1-Receptor Antagonists | FERRING B.V. (NL) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349629-A1 | Angiotensin-1-Receptor Antagonists | AGTR1, AGTR2, REN | SLC7A5 289/4885ALPI 3555/4885PKM 3664/4885 |
| US-20200102348-A1 | ANGIOTENSIN-1-RECEPTOR ANTAGONISTS | AGTR1, AGTR2, REN | SLC7A5 289/4885ALPI 3555/4885PKM 3664/4885 |
| US-10344054-B2 | Angiotensin-1-receptor antagonists | AGTR1, AGTR2, AGT | SLC7A5 392/4885ALPI 3362/4885PKM 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.