Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 18/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967128 | 0.93 | SLC6A9 (0.53) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL15967281 | 0.93 | SLC6A9 (0.59) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL15967136 | 0.92 | SLC6A9 (0.59) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL15967057 | 0.89 | SLC6A9 (0.58) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL15967315 | 0.89 | SLC6A9 (0.67) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL15967213 | 0.89 | SLC6A9 (0.60) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL15967321 | 0.88 | SLC6A9 (0.63) | SLC6A9KCNH2SLC6A5CYP3A4 | |
| SCHEMBL15967065 | 0.88 | SLC6A9 (0.52) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL712227 | 0.86 | SLC6A9 (0.67) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 | |
| SCHEMBL15967002 | 0.85 | SLC6A9 (0.61) | SLC6A9KCNH2SLC6A5CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |