Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 16/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 5/20 | 0.42 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967166 | 0.92 | SLC6A9 (0.64) | SLC6A9KCNH2SLC6A5GHSR | |
| Hydrochloric Acid SCHEMBL15967334 | 0.92 | SLC6A9 (0.72) | SLC6A9KCNH2SLC6A5GHSRCYP3A4 | |
| SCHEMBL15966913 | 0.89 | SLC6A9 (0.63) | SLC6A9KCNH2SLC6A5CYP3A4 | |
| SCHEMBL15967291 | 0.89 | SLC6A9 (0.59) | SLC6A9KCNH2SLC6A5GHSR | |
| SCHEMBL15967385 | 0.89 | SLC6A9 (0.72) | SLC6A9KCNH2SLC6A5GHSR | |
| SCHEMBL15967371 | 0.88 | SLC6A9 (0.73) | SLC6A9KCNH2SLC6A5CYP3A4 | |
| SCHEMBL15967152 | 0.88 | SLC6A9 (0.52) | SLC6A9KCNH2SLC6A5CYP3A4 | |
| SCHEMBL15967315 | 0.87 | SLC6A9 (0.67) | SLC6A9KCNH2SLC6A5CYP3A4 | |
| SCHEMBL709558 | 0.86 | SLC6A9 (0.85) | SLC6A9KCNH2SLC6A5CYP3A4 | |
| SCHEMBL15967065 | 0.85 | SLC6A9 (0.52) | SLC6A9KCNH2SLC6A5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |