SCHEMBL15967178

SCHEMBL15967178

CNC(=O)c1ccc(C(F)(F)F)[nH]c1=O

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 18/20 0.60
HSD17B1 P14061 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3088095 0.84 HSD17B2 (0.49) HSD17B2HSD17B1
SCHEMBL19616295 0.81 HSD17B2 (0.54) HSD17B2HSD17B1
SCHEMBL3056728 0.80 KDM4E (0.60) HSD17B2HSD17B1
SCHEMBL22867299 0.80 HSD17B2 (0.54) HSD17B2HSD17B1
SCHEMBL30359697 0.79 HSD17B2 (0.62) HSD17B2HSD17B1
SCHEMBL3077344 0.79 HSD17B2 (0.52) HSD17B2HSD17B1
SCHEMBL22867910 0.78 HSD17B1 (0.62) HSD17B2HSD17B1
SCHEMBL22867989 0.78 HSD17B2 (0.57) HSD17B2HSD17B1
SCHEMBL16830909 0.77 ALOX15 (0.41) HSD17B2HSD17B1
SCHEMBL19178226 0.77 HSD17B2 (0.51) HSD17B2HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1982978-B1 PYRIDONE DERIVATIVE AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO (JP) 2014-08-27 EP disclosed