Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.58 |
| ▸ | SLC6A5 | Q9Y345 | 7/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967292 | 0.91 | SLC6A9 (0.59) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15967057 | 0.90 | SLC6A9 (0.58) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15966974 | 0.88 | SLC6A9 (0.76) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15967013 | 0.87 | SLC6A9 (0.56) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15967385 | 0.86 | SLC6A9 (0.72) | SLC6A9KCNH2SLC6A5CYP2D6 | |
| SCHEMBL15967128 | 0.85 | SLC6A9 (0.53) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL710327 | 0.85 | SLC6A9 (0.76) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15966970 | 0.84 | SLC6A9 (0.58) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15967298 | 0.83 | SLC6A9 (0.68) | SLC6A9KCNH2SLC6A5CYP2D6CYP3A4 | |
| SCHEMBL15967120 | 0.83 | SLC6A9 (0.60) | SLC6A9KCNH2SLC6A5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |