Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 14/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967166 | 0.94 | SLC6A9 (0.64) | SLC6A9KCNH2SLC6A5CYP2D6GHSR | |
| SCHEMBL15967371 | 0.92 | SLC6A9 (0.73) | SLC6A9KCNH2SLC6A5CYP2D6SLC6A4 | |
| SCHEMBL15967125 | 0.91 | SLC6A9 (0.58) | SLC6A9KCNH2SLC6A5CYP2D6 | |
| Hydrochloric Acid SCHEMBL15967334 | 0.90 | SLC6A9 (0.72) | SLC6A9KCNH2SLC6A5GHSR | |
| SCHEMBL15967291 | 0.90 | SLC6A9 (0.59) | SLC6A9KCNH2SLC6A5GHSRALDH1A1 | |
| SCHEMBL15967208 | 0.90 | SLC6A9 (0.61) | SLC6A9KCNH2SLC6A5GHSRALDH1A1 | |
| SCHEMBL15967321 | 0.89 | SLC6A9 (0.63) | SLC6A9KCNH2SLC6A5GHSR | |
| SCHEMBL15967120 | 0.89 | SLC6A9 (0.60) | SLC6A9KCNH2SLC6A5CYP2D6 | |
| SCHEMBL15966963 | 0.88 | SLC6A9 (0.59) | SLC6A9KCNH2SLC6A5CYP2D6 | |
| SCHEMBL15967337 | 0.88 | SLC6A9 (0.73) | SLC6A9KCNH2SLC6A5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |