Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL708457 | 0.99 | OPRM1 (0.53) | OPRM1OPRD1OPRK1P2RX7KCNH2 | |
| SCHEMBL3776499 | 0.86 | CACNA1H (0.49) | OPRM1OPRD1OPRK1P2RX7KCNH2 | |
| SCHEMBL5510482 | 0.85 | CACNA1H (0.61) | P2RX7KCNH2CACNA1IRAB9ACACNA1H | |
| SCHEMBL708595 | 0.82 | MEN1 (0.52) | — | |
| SCHEMBL5506769 | 0.82 | HPGD (0.54) | OPRM1OPRK1KCNH2CACNA1INPC1 | |
| SCHEMBL15967240 | 0.81 | KCNH2 (0.47) | OPRM1OPRK1KCNH2CACNA1ICACNA1H | |
| Hydrochloric Acid SCHEMBL709864 | 0.80 | KCNH2 (0.46) | OPRM1OPRK1KCNH2CACNA1ICACNA1H | |
| SCHEMBL5513102 | 0.80 | POLB (0.56) | TP53NAMPT | |
| Hydrochloric Acid SCHEMBL709535 | 0.79 | POLB (0.55) | TP53NAMPT | |
| SCHEMBL15967030 | 0.78 | EPHX2 (0.53) | P2RX7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |