Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL708458 | 0.99 | CHRM2 (0.49) | CHRM2CXCR4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15967032 | 0.89 | TAAR1 (0.49) | CHRM2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3776502 | 0.86 | CHRM2 (0.43) | CHRM2CXCR4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5510485 | 0.84 | PRMT5 (0.37) | CHRM2CXCR4HTR2C | |
| SCHEMBL708596 | 0.81 | CXCR4 (0.46) | CXCR4HTR2C | |
| SCHEMBL5506772 | 0.81 | PRMT5 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL3770111 | 0.80 | CXCR4 (0.49) | CHRM2CXCR4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15967241 | 0.80 | PRMT5 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19HDAC1 | |
| SCHEMBL5513104 | 0.79 | DPP7 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19NOS1 | |
| Hydrochloric Acid SCHEMBL709865 | 0.79 | PRMT5 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |