Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342325 | 1.00 | PSEN1 (0.31) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2511023 | 0.94 | — | — | |
| SCHEMBL21628076 | 0.86 | — | — | |
| SCHEMBL2368119 | 0.86 | PTGS1 (0.34) | — | |
| SCHEMBL2431617 | 0.84 | MGLL (0.30) | — | |
| SCHEMBL7559924 | 0.84 | PTGS1 (0.30) | — | |
| SCHEMBL28366699 | 0.82 | — | — | |
| SCHEMBL28933685 | 0.82 | ALDH1A1 (0.43) | — | |
| SCHEMBL10446959 | 0.81 | PSEN1 (0.31) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4974653 | 0.80 | PTGS1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140242073-A1 | CARTILAGE/BONE DESTRUCTION SUPPRESSOR | KAGOSHIMA UNIVERSITY (JP) | 2014-08-28 | — | — | US | disclosed |