Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15969265 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL15983489 | 0.83 | CDC25A (0.83) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL13831597 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL15969696 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL15983520 | 0.80 | ALDH1A1 (0.83) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL6408220 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL13831599 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL22046629 | 0.79 | ALDH1A1 (0.79) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL13737457 | 0.78 | KMT2A (0.69) | ALDH1A1KMT2AMEN1POLBCDC25A | |
| SCHEMBL18556544 | 0.77 | KMT2A (0.58) | ALDH1A1KMT2AMEN1POLBCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | OR51E2, TRPA1, OR10J3 | ALDH1A1 3549/4885KMT2A 4216/4885MEN1 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.