Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284075 | 0.77 | TET2 (0.48) | ALDH1A1LMNAMEN1KMT2ATET2 | |
| SCHEMBL9457498 | 0.73 | — | — | |
| SCHEMBL27729676 | 0.71 | — | — | |
| SCHEMBL27687085 | 0.71 | — | — | |
| SCHEMBL8248295 | 0.71 | RECQL (0.45) | LMNAKMT2ATET2RECQLNPC1 | |
| SCHEMBL11504339 | 0.70 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AEPHX1RECQL | |
| SCHEMBL757885 | 0.70 | TET2 (0.50) | ALDH1A1LMNATET2RECQLTSHR | |
| SCHEMBL12694105 | 0.70 | TET2 (0.61) | ALDH1A1LMNAMEN1KMT2ATET2 | |
| SCHEMBL14489950 | 0.69 | MEN1 (0.57) | ALDH1A1LMNAMEN1KMT2AEPHX1 | |
| SCHEMBL12057423 | 0.69 | GAA (0.46) | ALDH1A1LMNAMEN1KMT2ATET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919630-B2 | Synthesis of imidazole 2-thiones via thiohydantoins | ALLERGAN, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20070203344-A1 | SYNTHESIS OF IMIDAZOLE 2-THIONES VIA THIOHYDANTOINS | ALLERGAN, INC. | 2007-08-30 | — | — | US | disclosed |
| WO-2007041048-A2 | SYNTHESIS OF IMIDAZOLE-2-THIONES VIA THIOHYDANTOINS | ALLERGAN, INC. (US) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203344-A1 | SYNTHESIS OF IMIDAZOLE 2-THIONES VIA THIOHYDANTOINS | TPMT, NISCH, IMPDH2 | ALDH1A1 784/4885LMNA 4607/4885MEN1 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.