Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.58 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.58 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.58 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15970702 | 1.00 | MAPT (0.69) | MAPTALDH1A1TRPV1KMT2ALMNA | |
| SCHEMBL10084157 | 0.86 | ALDH1A1 (0.73) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11568800 | 0.85 | MAPT (0.65) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11568796 | 0.85 | MAPT (0.65) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL22422964 | 0.85 | ALDH1A1 (0.77) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11573961 | 0.82 | MAPT (0.60) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11573963 | 0.82 | MAPT (0.60) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL14360894 | 0.81 | MAPT (0.87) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL14360890 | 0.81 | MAPT (0.87) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL30925683 | 0.81 | APP (0.75) | MAPTALDH1A1KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014129874-A1 | PIPER AMIDE-BASED COMPOUND AS BOMBESIN RECEPTOR SUBTYPE 3 | 서울대학교산학협력단 (KR) | 2014-08-28 | — | — | WO | disclosed |