Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717546 | 0.84 | CES1 (0.38) | ALDH1A1HTTTSHRSMN1; SMN2RXRA | |
| SCHEMBL31146135 | 0.84 | THRB (0.35) | KDM4EHSD17B10ALDH1A1HPGDKEAP1 | |
| SCHEMBL19687793 | 0.80 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1HPGDKEAP1 | |
| SCHEMBL24805151 | 0.80 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1HPGDKEAP1 | |
| SCHEMBL21750024 | 0.78 | KEAP1 (0.45) | KDM4EHSD17B10ALDH1A1HPGDKEAP1 | |
| SCHEMBL2203971 | 0.76 | KEAP1 (0.44) | KDM4EHSD17B10ALDH1A1KEAP1KMT2A | |
| SCHEMBL16416613 | 0.73 | KEAP1 (0.46) | KDM4EHSD17B10ALDH1A1HPGDKEAP1 | |
| SCHEMBL15978622 | 0.73 | CYP3A4 (0.41) | KDM4EHSD17B10ALDH1A1KEAP1KMT2A | |
| SCHEMBL15352673 | 0.73 | KEAP1 (0.41) | KDM4EHSD17B10ALDH1A1KEAP1KMT2A | |
| SCHEMBL9769391 | 0.73 | HSD17B10 (0.39) | KDM4EHSD17B10ALDH1A1HPGDKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2014128612-A1 | QUINAZOLIN-4-ONE DERIVATIVES | NOVARTIS AG (CH) | 2014-08-28 | — | — | WO | disclosed |