⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15973100 | 0.86 | ADH1B (0.34) | — | |
| SCHEMBL1300950 | 0.85 | — | — | |
| SCHEMBL1836510 | 0.85 | — | — | |
| SCHEMBL14434326 | 0.85 | — | — | |
| SCHEMBL10045710 | 0.82 | — | — | |
| SCHEMBL27048229 | 0.80 | EPHX2 (0.38) | — | |
| SCHEMBL24017656 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL9047999 | 0.76 | — | — | |
| SCHEMBL76463 | 0.76 | — | — | |
| SCHEMBL6379288 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958897-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2014130582-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2014-08-28 | — | — | WO | disclosed |