Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 13/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061469 | 0.75 | KMT2A (0.58) | EPHX1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL12196114 | 0.74 | EPHX1 (0.56) | EPHX1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL13446569 | 0.72 | ALDH1A1 (0.39) | SMN1; SMN2KMT2AALDH1A1KDM4E | |
| SCHEMBL13756244 | 0.70 | EPHX1 (0.86) | EPHX1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL13446573 | 0.68 | ABL1 (0.40) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13411743 | 0.68 | CDK2 (0.40) | EPHX1SMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL24308699 | 0.68 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL15093798 | 0.68 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL24308701 | 0.68 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2MEN1 | |
| 1,3-Dicyclohexylurea SCHEMBL2755 | 0.68 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815951-B2 | Inhibitors of epoxide hydrolases for the treatment of inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |