Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.53 |
| ▸ | PGK2 | P07205 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975256 | 1.00 | PGK1 (0.53) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL15975273 | 0.88 | PGK1 (0.48) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL15975534 | 0.88 | PGK1 (0.48) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL15975533 | 0.86 | NR1I2 (0.55) | PDE4D | |
| SCHEMBL15496606 | 0.86 | NR1I2 (0.55) | PDE4D | |
| SCHEMBL15496605 | 0.86 | PGK1 (0.45) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL15975543 | 0.86 | PGK1 (0.45) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL31006732 | 0.86 | PGK1 (0.45) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL15496601 | 0.83 | LMNA (0.55) | ADORA3PNPLMNATP53HTT | |
| SCHEMBL15499076 | 0.83 | LMNA (0.55) | ADORA3PNPLMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815829-B2 | 3′-azido purine nucleotide prodrugs for treatment of viral infections | RFS PHARMA, LLC (US) | 2014-08-26 | — | — | US | disclosed |