Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499995 | 1.00 | ITGB3 (0.54) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL18697439 | 0.96 | ITGB3 (0.57) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL20146949 | 0.96 | ITGB3 (0.57) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL18697434 | 0.96 | ITGB3 (0.57) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL14725963 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL20652774 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL17244041 | 0.92 | GLP1R (0.53) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL24652677 | 0.92 | GLP1R (0.59) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL12497136 | 0.92 | GLP1R (0.59) | ITGB3ITGA2BTP53TSHRPLA2G4B | |
| SCHEMBL12496872 | 0.92 | GLP1R (0.59) | ITGB3ITGA2BTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815802-B2 | GLP-1 analogues and derivatives | NOVO NORDISK A/S (DK) | 2014-08-26 | — | — | US | disclosed |