SCHEMBL20146949

CCCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CCCCCCCCCCCOc1ccc(C(=O)O)cc1)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ITGB3	P05106	2/20	0.57

▸	ITGA2B	P08514	2/20	0.57

▸	TP53	P04637	1/20	0.55

▸	TSHR	P16473	1/20	0.55

▸	PLA2G4B	P0C869	5/20	0.54

▸	NOD1	Q9Y239	2/20	0.53

▸	RARB	P10826	3/20	0.52

▸	GLP1R	P43220	4/20	0.52

▸	PLA2G4A	P47712	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18697434	1.00	ITGB3 (0.57)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL18697439	1.00	ITGB3 (0.57)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL20652774	0.96	ITGB3 (0.53)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL15975845	0.96	ITGB3 (0.54)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL12499995	0.96	ITGB3 (0.54)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL14725963	0.93	ITGB3 (0.54)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL17244041	0.92	GLP1R (0.53)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL16455544	0.92	GLP1R (0.63)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL20652754	0.92	GLP1R (0.63)	ITGB3ITGA2BTP53TSHRPLA2G4B
SCHEMBL19152613	0.92	GLP1R (0.63)	ITGB3ITGA2BTP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2637699-B1	DOUBLE-ACYLATED GLP-1 DERIVATIVES WITH A LINKER	NOVO NORDISK AS (DK)	2018-05-16	—	—	EP	disclosed