SCHEMBL15977141

SCHEMBL15977141

Cc1c(C)c(C)c(-c2ccc(F)cc2)c(C)c1C

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.48
SENP1 Q9P0U3 1/20 0.42
GCGR P47871 1/20 0.41
PTGS2 P35354 6/20 0.39
KDM4E B2RXH2 1/20 0.38
TNKS2 Q9H2K2 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NFE2L2 Q16236 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TYMP P19971 1/20 0.36
PTGS1 P23219 1/20 0.36
BCL2L1 Q07817 1/20 0.36
BAD Q92934 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13866713 0.84 ACHE (0.39) ACHESENP1GCGRPTGS2KDM4E
SCHEMBL11860703 0.74 ACHE (0.47) ACHESENP1PTGS2KMT2A
SCHEMBL30507348 0.74 MGAM (0.46) ACHEKDM4ETNKS2NPC1RAB9A
SCHEMBL13791048 0.74 PTGS2 (0.41) ACHEGCGRPTGS2KDM4ENPC1
SCHEMBL21937382 0.72 MEN1 (0.43) ACHEGCGRPTGS2KDM4ENPC1
SCHEMBL30507312 0.72 ACHE (0.48) ACHEPTGS2KDM4ETNKS2NFE2L2
SCHEMBL10337645 0.71 BCL2L1 (0.55) ACHENPC1RAB9ABCL2L1BAD
SCHEMBL12562793 0.71 BCL2L1 (0.55) ACHENPC1RAB9ABCL2L1BAD
SCHEMBL197346 0.71 BCL2L1 (0.55) ACHENPC1RAB9ABCL2L1BAD
SCHEMBL10300262 0.71 BCL2L1 (0.55) ACHENPC1RAB9ABCL2L1BAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2980876-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE, DISPLAY DEVICE, LIGHT-EMITTING THIN FILM AND COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING METHOD Konica Minolta, Inc. (JP) 2016-02-03 EP disclosed
EP-1786242-B1 ORGANIC ELECTROLUMINESCENCE DEVICE, DISPLAY APPARATUS AND LIGHTING APPARATUS KONICA MINOLTA HOLDINGS INC (JP) 2014-08-27 EP disclosed