Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.66 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.54 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25512689 | 0.89 | L3MBTL1 (0.61) | L3MBTL1CHRNA7SIRT2CYP1A2CYP2D6 | |
| Dehydrostobadine SCHEMBL167500 | 0.88 | L3MBTL1 (0.97) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 | |
| Dehydrostobadine SCHEMBL29468212 | 0.88 | L3MBTL1 (0.97) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 | |
| SCHEMBL18034956 | 0.88 | KDM4E (0.66) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 | |
| Dehydrostobadine SCHEMBL2837548 | 0.87 | L3MBTL1 (1.00) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 | |
| Dehydrostobadine SCHEMBL3715610 | 0.87 | L3MBTL1 (1.00) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 | |
| SCHEMBL2185371 | 0.84 | CHRNA7 (0.64) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 | |
| SCHEMBL27099161 | 0.84 | CHRNA7 (0.64) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 | |
| SCHEMBL168351 | 0.84 | CHRNA7 (0.64) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 | |
| SCHEMBL167846 | 0.82 | CHRNA7 (0.62) | L3MBTL1CHRNA7SIRT2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |
| EP-2476680-B1 | (1-Azinone)-Substituted Pyridoindoles | ALBANY MOLECULAR RES INC (US) | 2014-08-27 | — | — | EP | disclosed |