SCHEMBL15977207

SCHEMBL15977207

Cc1cccc2c1[C@]1(CC2)CCc2cccc(P)c21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR5A P47898 1/20 0.33
CD44 P16070 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15222152 0.80 CD44 (0.47) HTR5ACD44
SCHEMBL15268227 0.80 KDM4E (0.36) CD44
SCHEMBL15868752 0.76 PNMT (0.37) HTR5ACD44
SCHEMBL15868753 0.75 TSHR (0.44) HTR5A
SCHEMBL15868756 0.72 SLC6A4 (0.36)
SCHEMBL15268226 0.71 DRD1 (0.40)
SCHEMBL16449686 0.71 DRD1 (0.40)
SCHEMBL25027774 0.71 CD44 (0.38) HTR5ACD44
SCHEMBL22989888 0.69 HTR5A (0.37) HTR5ACD44
SCHEMBL12670552 0.67 SMN1; SMN2 (0.34) HTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272853-B1 SPIRO PHOSPHORUS-OXAZOLINE, SYNTHESIS AND USE THEREOF ZHEJIANG JIUZHOU PHARM CO LTD (CN) 2014-08-27 EP disclosed